Publications

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2012
Grünberger A, van Ooyen J, Paczia N, Rohe P, Schiendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S. Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments. Biotechnol Bioeng. 2012.
Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D. A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level. Lab Chip. 2012;12(11):2060-8.
2013
Probst C, Grünberger A, Wiechert W, Kohlheyer D. Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes. J Microbiol Methods. 2013;95(3):470-6.
Probst C, Grünberger A, Wiechert W, Kohlheyer D. Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria. Micromachines. 2013;4(4):357-369.
2014
Nanda AM, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J. Analysis of SOS-induced spontaneous prophage induction in Corynebacterium glutamicum at the single-cell level. J Bacteriol. 2014;196(1):180-8.
Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J. Application of a genetically encoded biosensor for live cell imaging of L-valine production in pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum strains. PLoS One. 2014;9(1):e85731.
Unthan S, Grünberger A, van Ooyen J, Gätgens J, Heinrich J, Paczia N, Wiechert W, Kohlheyer D, Noack S. Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium. Biotechnol Bioeng. 2014;111(2):359-71.
Grünberger A, Wiechert W, Kohlheyer D. Single-cell microfluidics: opportunity for bioprocess development. Curr Opin Biotechnol. 2014;29C:15-23.
2015
Helfrich S, Pfeifer E, Krämer C, Sachs CC, Wiechert W, Kohlheyer D, Nöh K, Frunzke J. Live cell imaging of SOS and prophage dynamics in isogenic bacterial populations. Mol Microbiol. 2015.
Grünberger A, Probst C, Helfrich S, Nanda A, Stute B, Wiechert W, von Lieres E, Nöh K, Frunzke J, Kohlheyer D. Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform. Cytometry A. 2015.
Helfrich S, Azzouzi CE, Probst C, Seiffarth J, Grünberger A, Wiechert W, Kohlheyer D, Nöh K. Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics. 2015.
2016
Sachs CC, Grünberger A, Helfrich S, Probst C, Wiechert W, Kohlheyer D, Nöh K. Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments. PLoS One. 2016;11(9):e0163453.
Pfeifer E, Hünnefeld M, Popa O, Polen T, Kohlheyer D, Baumgart M, Frunzke J. Silencing of cryptic prophages in Corynebacterium glutamicum. Nucleic Acids Res. 2016;44(21):10117-10131.
2018
Kampf J, Gerwig J, Kruse K, Cleverley R, Dormeyer M, Grünberger A, Kohlheyer D, Commichau FM, Lewis RJ, Stülke J. Selective pressure for biofilm formation in Bacillus subtilis: differential effect of mutations in the master regulator SinR on bistability. mBio. 2018;9:e00166-18.
Vilhena C, Kaganovitch E, Shin JY, Grünberger A, Behr S, Kristoficova I, Brameyer S, Kohlheyer D, Jung K. A single cell view of the BtsSR/YpdAB pyruvate sensing network in Escherichia coli and its biological relevance. J. Bacteriol. 2018;200:e00536-17.
2019
Vilhena C, Kaganovitch E, Grünberger A, Motz M, Forné I, Kohlheyer D, Jung K. Importance of pyruvate sensing and transport for the resuscitation of viable but nonculturable Escherichia coli K-12. J. Bacteriol. 2019;201:e00610-18.