Publications
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α-Hydroxyketone synthesis and sensing by Legionella and Vibrio. Sensors (Basel). 2012;12(3):2899-919.
. The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila. Mol Microbiol. 2016;99:778-793.
. Synergistic contribution of the Legionella pneumophila lqs genes to pathogen-host interactions. J Bacteriol. 2008;190(22):7532-47.
. Phosphorylation signalling through the Legionella quorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR. Mol Microbiol. 2014;92(5):1039-55.
. Pathway analysis using 13C-glycerol and other carbon tracers reveals bipartite metabolism of Legionella pneumophila. Mol. Microbiol. 2016;100:229-246.
. Metabolism of myo-inositol by Legionella pneumophila promotes infection of amoeba and macrophages. Appl. Environ. Micro. 2016;82:5000-5014.
. The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell Microbiol. 2007;9(12):2903-20.
. The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit. Environ Microbiol. 2012.
. The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit. Environ. Microbiol. 2013;15:646-662.
. The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule. J Biol Chem. 2008;283(26):18113-23.
. Inter-kingdom signaling by the Legionella quorum sensing molecule LAI-1 inhibits cell migration through an IQGAP1/CDC42/ARHGEF9-dependent pathway. PLoS Pathog. 2015;11:e1005307.
. Bacterial gene regulation by alpha-hydroxyketone signaling. Trends Microbiol. 2010;18(7):288-97.
. The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila. Environ Microbiol. 2010;12(5):1243-59.
. Autoinducers Act as Biological Timers in Vibrio harveyi. PLoS One. 2012;7(10):e48310.
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