Publications

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2016
Manske C, Schell U, Hilbi H. Metabolism of myo-inositol by Legionella pneumophila promotes infection of amoeba and macrophages. Appl. Environ. Micro. 2016;82:5000-5014.
Häuslein I, Manske C, Goebel W, Eisenreich W, Hilbi H. Pathway analysis using 13C-glycerol and other carbon tracers reveals bipartite metabolism of Legionella pneumophila. Mol. Microbiol. 2016;100:229-246.
Schell U, Simon S, Sahr T, Hager D, Albers MF, Kessler A, Fahrnbauer F, Trauner D, Hedberg C, Buchrieser C. The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila. Mol Microbiol. 2016;99:778-793.
2015
Simon S, Schell U, Heuer N, Hager D, Albers MF, Matthias J, Fahrnbauer F, Trauner D, Eichinger L, Hedberg C. Inter-kingdom signaling by the Legionella quorum sensing molecule LAI-1 inhibits cell migration through an IQGAP1/CDC42/ARHGEF9-dependent pathway. PLoS Pathog. 2015;11:e1005307.
2014
Schell U, Kessler A, Hilbi H. Phosphorylation signalling through the Legionella quorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR. Mol Microbiol. 2014;92(5):1039-55.
2013
Kessler A, Schell U, Sahr T, Tiaden A, Harrison C, Buchrieser C, Hilbi H. The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit. Environ. Microbiol. 2013;15:646-662.
2012
Anetzberger C, Reiger M, Fekete A, Schell U, Stambrau N, Plener L, Kopka J, Schmitt-Kopplin P, Hilbi H, Jung K. Autoinducers Act as Biological Timers in Vibrio harveyi. PLoS One. 2012;7(10):e48310.
Kessler A, Schell U, Sahr T, Tiaden A, Harrison C, Buchrieser C, Hilbi H. The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit. Environ Microbiol. 2012.
Tiaden A, Hilbi H. α-Hydroxyketone synthesis and sensing by Legionella and Vibrio. Sensors (Basel). 2012;12(3):2899-919.
2010
Tiaden A, Spirig T, Sahr T, Wälti MA, Boucke K, Buchrieser C, Hilbi H. The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila. Environ Microbiol. 2010;12(5):1243-59.
Tiaden A, Spirig T, Hilbi H. Bacterial gene regulation by alpha-hydroxyketone signaling. Trends Microbiol. 2010;18(7):288-97.
2008
Spirig T, Tiaden A, Kiefer P, Buchrieser C, Vorholt JA, Hilbi H. The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule. J Biol Chem. 2008;283(26):18113-23.
Tiaden A, Spirig T, Carranza P, Brüggemann H, Riedel K, Eberl L, Buchrieser C, Hilbi H. Synergistic contribution of the Legionella pneumophila lqs genes to pathogen-host interactions. J Bacteriol. 2008;190(22):7532-47.
2007
Tiaden A, Spirig T, Weber SS, Brüggemann H, Bosshard R, Buchrieser C, Hilbi H. The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell Microbiol. 2007;9(12):2903-20.