@article {11,
title = {Approximate genealogies under genetic hitchhiking.},
journal = {Genetics},
volume = {174},
year = {2006},
month = {2006 Dec},
pages = {1995-2008},
abstract = {The rapid fixation of an advantageous allele leads to a reduction in linked neutral variation around the target of selection. The genealogy at a neutral locus in such a selective sweep can be simulated by first generating a random path of the advantageous allele{\textquoteright}s frequency and then a structured coalescent in this background. Usually the frequency path is approximated by a logistic growth curve. We discuss an alternative method that approximates the genealogy by a random binary splitting tree, a so-called Yule tree that does not require first constructing a frequency path. Compared to the coalescent in a logistic background, this method gives a slightly better approximation for identity by descent during the selective phase and a much better approximation for the number of lineages that stem from the founder of the selective sweep. In applications such as the approximation of the distribution of Tajima{\textquoteright}s D, the two approximation methods perform equally well. For relevant parameter ranges, the Yule approximation is faster.},
keywords = {Alleles, Animals, Crossing Over, Genetic, Genealogy and Heraldry, Gene Frequency, Humans, Models, Genetic, Models, Theoretical, Selection, Genetic},
issn = {0016-6731},
doi = {10.1534/genetics.106.061887},
author = {Pfaffelhuber, Peter and Haubold, B and Wakolbinger, A}
}